Ask Dr. Renée: Peptide Serums vs Peptide Creams

BodySep 9, 2025

As you master the art of glowing up, you might have to face a pivotal decision: Serum or cream? The debate rages on, but we’re about to decode two of skincare’s most beloved formulas with one powerhouse ingredient in mind — peptides. Those tiny but mighty warriors are in high demand, but do you layer them on as a hydrating cream or pave the way with a penetrating peptide serum?

We’ve got questions, Dr. Renée’s got answers, and we’re about to unlock the secrets of our Truly Becoming Peptide Serum and the new game-changing Firm Belief Peptide Cream. Get ready to level up your skincare game and set the vibes to ‘glow,’ with a Q&A that might change your skincare routine forever.

DIFFERENCE BETWEEN PEPTIDE SERUM AND PEPTIDE MOISTURIZER

Peptide serums are typically more of a lightweight product that is in a thin or gel-like vehicle that absorbs quickly into the skin. They are typically highly concentrated with active ingredients to address specific skin concerns, such as dullness or, in the case of the peptide serum, reduces the appearance of wrinkles.

Peptide moisturizers primarily provide hydration and help maintain the skin’s moisture levels, they contain a mixture of hydrating ingredients like emollients, occlusives and humectants. Typically, moisturizers are the final step of a skincare routine to seal in the benefits of previous products applied and provide a barrier for the skin. Don’t forget to give your neck some love with this nourishing moisturizer.

SPILL THE TEA ON KEYS SOULCARE’S TRULY BECOMING PEPTIDE SERUM AND THE NEW FIRM BELIEF PEPTIDE CREAM. WHAT MAKES THEM THE MVPS IN OUR SKINCARE LINEUP?

Peptides are known to help aging skin by smoothing and firming the appearance of fine lines and wrinkles.

The Firm Belief Smoothing Peptide Cream compliments our Truly Becoming Peptide Serum with a multi-peptide complex to smooth the appearance of fine lines and wrinkles. Snow mushroom added to the cream helps to hydrate and visibly plump the skin. Fermented astralagus extract elevates this offering as an adaptogenic used in traditional Chinese medicine to improve the feel of skin firmness.

WHAT DO PEPTIDES DO FOR YOUR SKIN?

Consider your specific skincare needs and goals when incorporating peptides into your routine. Using multiple peptides for skin may be beneficial if you’re targeting multiple skin concerns, such as the appearance and feel of wrinkles, fine lines, firmness, and hydration. The quality of our peptide formulas play a significant role in their effectiveness. Truly Becoming is a lightweight, hydrating formula perfect for maturing skin. While both offerings help hydrate skin, the Firm Belief Peptide Cream is best for someone with more dehydrated skin. Regardless of what you choose, consistency is key if these offerings are incorporated into your daily ritual.

DAY OR NIGHT — WHEN TO USE PEPTIDE SERUM AND MOISTURIZER?

The beauty of incorporating peptides into a skin care regimen is that it compliments any morning and evening regimen. Consistency in your skincare ritual is key. Using peptides in the morning helps reduce the appearance of fine lines and wrinkles, creating a smoother-looking complexion throughout the day.

Our skin typically goes through a natural repair and regeneration process while you are asleep. Skin regeneration is a process that occurs during cell turnover. Applying peptides at night can enhance and improve skin tone and texture.

WHEN WE CAN EXPECT THAT INSTA-WORTHY GLOW WHEN USING A PEPTIDE CREAM OR SERUM?

While our serum has clinic reports that cite 97% of users saw an instant improvement in appearance of lines and wrinkles and 100% experienced improvement in 7 days, significant lasting improvements typically require time, consistency and patience. I personally like to encourage and focus on long-term skin benefits rather than instant transformations.

WHAT’S A PRO TIP TO MAKE THE MOST OUT OF OUR SKINCARE RITUAL AND OWN OUR GLOW?

Understand your skin type and concerns, develop a consistent ritual, cleanse thoroughly, apply active ingredients from a trusted source, and use sun protection daily. Last, but certainly not least, be patient and consistent. Own your glow by taking the time to love yourself, which will allow you to love others and shine at full wattage.

Have you tried both Keys Soulcare offerings? Leave your reviews in the comments!